Is this you? As a journalist, you can create a free Muck Rack account to customize your profile, list your contact preferences, and upload a portfolio of your best work.
Claim your profile
Articles by Jan Hedner
Sleep duration and insomnia symptoms in relation to lung function in the Swedish CArdioPulmonary BioImage Study (SCAPIS): a cross-sectional study
Abstract Sleep duration and insomnia symptoms are linked to adverse cardiometabolic outcomes, but associations with lung function remain unclear. Are sleep duration and insomnia symptoms associated with post-bronchodilator lung function and chronic airflow limitation (CAL)?. Post-bronchodilator FEV₁, FVC, FEV₁/FVC and DLCO were measured in a cross-sectional analysis of 27,740 participants (women 52%, mean age 57 years) from the Swedish CArdioPulmonary bioImage Study (SCAPIS).
Long-range interdependencies aware signal analysis for rapid and accurate obstructive sleep apnea prediction
|
Abstract Obstructive sleep apnea, characterized by frequent interruptions in breathing and intermittent hypoxia, is a public health concern due to its potential to increase multiple organ system morbidity and mortality. Although polysomnography is the gold standard for diagnosis, it is laborious, costly, and complex. Here, we present a biological geometry-aware artificial intelligence framework that processes physiological signals to predict sleep apnea severity.
By Zhenkun Wang, Xinghe Chen, Mingxi Cheng, Haoqing Wang, Haofan Sun, Stefan A. Mihaicuta, Lucretia Udrescu, David Gozal, Félix del Campo, Fernando Vaquerizo-Villar, Roberto Hornero, Jan Hedner, Winfried Randerath, David M. Mannino, Shahin Nazarian, Mihai Udrescu, Paul Bogdan, Chenzhong Yin, Anzhe Cheng
|
Nature
Verified
Sulthiame decreases breathing pauses during sleep, daytime sleepiness score in OSA
You've successfully added to your alerts. You will receive an email when new content is published. Click Here to Manage Email Alerts We were unable to process your request. Please try again later. If you continue to have this issue please contact customerservice@slackinc.com. Key takeaways: The 300 mg sulthiame group had a 39.9% decrease in apnea-hypopnea index 3a at week 15. Other factors that improved among those receiving sulthiame included sleep quality and Epworth sleepiness scale scores.
Hypertension treatment in patients with sleep apnea from the European Sleep Apnea Database (ESADA) cohort - towards precision medicine
4 DISCUSSION Our study identified OSA patient characteristics where use of beta-blocker treatment alone or in combination with diuretics was associated with significantly better BP when compared with patients using other antihypertensive medication. In particular, we report for the first time that easily identifiable factors like gender, age, non-obesity, and sleep apnea intensity are associated with lower BP in patients with these treatments.
A Randomized Controlled Clinical Trial Exploring Safety and Tolerability of Sulthiame in Sleep Apnea
Statistical Analysis Sample-size calculation in this safety and tolerability study was based on available literature data assessing the effect of CA inhibitors on mean AHI reduction in patients with OSA (Tables E3 and E4). A total sample size of 96 patients, corresponding to six cohorts, was computed to achieve at least 80% power. However, regarding treatment efficacy, this was an exploratory study intended to support the planning of confirmatory phase III trials.
European Respiratory Society guideline on non-CPAP therapies for obstructive sleep apnoea
Winfried Randerath, Johan Verbraecken, Christel A.L. de Raaff, Jan Hedner, Simon Herkenrath, Winfried Hohenhorst, Tina Jakob, Oreste Marrone, Marie Marklund, Walter T. McNicholas, Rebecca L.
Positive airway pressure (PAP) treatment reduces glycated hemoglobin (HbA1c) levels in obstructive sleep apnea patients with concomitant weight loss: Longitudinal data from the ESADA
REGULAR RESEARCH PAPER Mehmet Sezai Tasbakan Corresponding Author sezai.tasbakan@ege.edu.tr sezai72000@yahoo.com orcid.org/0000-0003-4507-9851 Department of Chest Diseases, Ege University Faculty of Medicine, Izmir, Turkey Correspondence Mehmet Sezai Tasbakan, Department of Chest Disease, Faculty of Medicine, Ege University, Izmir, Turkey.
Evaluation of a multicomponent grading system for obstructive sleep apnoea: the Baveno classification
Winfried J. Randerath, Simon Herkenrath, Marcel Treml, Ludger Grote, Jan Hedner, Maria Rosaria Bonsignore, Jean Louis Pépin, Silke Ryan, Sophia Schiza, Johan Verbraecken, Walter T. McNicholas, Athanasia Pataka, Pawel Sliwinski, Özen K.
Insomnia is associated with metabolic syndrome in a middle-aged population: the SCAPIS pilot cohort
The metabolic syndrome (MetS) represents a cluster of risk factors for cardiovascular disease (CVD) and type 2 diabetes, including central obesity, reduced high-density lipoprotein (HDL) cholesterol, elevated triglycerides, blood pressure and fasting plasma glucose.
The European Sleep Apnoea Database (ESADA) ERS Clinical Research Collaboration: past, present and future
Collaborators: M.R. Bonsignore and J. Hedner are Chairs of the ESADA Clinical Research Collaboration. Collaborators in the ESADA project (current and past) by country and sleep centre were as follows. Belgium: J. Verbraecken and E. Petiet (Multidisciplinary Sleep Disorders Centre, Antwerp University Hospital and University of Antwerp, Antwerp); D. Rodenstein (Cliniques Universitaires Saint-Luc, Brussels). Croatia: Z. Dogas and T.
Certification of fitness to drive in sleep apnea patients: Are we doing the right thing?
New European Union (EU) regulations state that untreated moderate to severe obstructive sleep apnea (OSA) coincident with excessive daytime sleepiness (EDS) constitutes a medical disorder leading to unfitness to drive. However, fitness to drive can be re‐established by successful treatment of OSA and EDS. The aim of the current study was to compare patients undergoing the certification process with those of an unselected OSA patient cohort.
Change in weight and central obesity by positive airway pressure treatment in obstructive sleep apnea patients: longitudinal data from the ESADA cohort - Basoglu - - Journal of Sleep Research - Wiley Online Library
The effect of positive airway pressure treatment on weight and markers of central obesity in patients with obstructive sleep apnea remains unclear. We studied the change in body weight and anthropometric measures following positive airway pressure treatment in a large clinical cohort.
Recommendations for the management of patients with obstructive sleep apnoea and hypertension
Abstract This article is aimed at addressing the current state-of-the-art in epidemiology, pathophysiology, diagnostic procedures and treatment options for appropriate management of obstructive sleep apnoea (OSA) in cardiovascular (in particular hypertensive) patients, as well as for the management of cardiovascular diseases (in particular arterial hypertension) in OSA patients.
Pre-operative screening for obstructive sleep apnoea
AbstractSleep disordered breathing, especially obstructive sleep apnoea (OSA), has a high and increasing prevalence. Depending on the apnoea and hypopnoea scoring criteria used, and depending on the sex and age of the subjects investigated, prevalence varies between 3% and 49% of the general population. These varying prevalences need to be reflected when considering screening for OSA. OSA is a cardiovascular risk factor and patients are at risk when undergoing medical interventions such as surgery.
A randomised, open-label, crossover study of the dopamine agonist, pramipexole, in patients with sleep bruxism
Sleep bruxism bears several similarities to restless legs syndrome, and a link to changes in central dopamine activity has been considered in both conditions. The dopamine agonist pramipexole is currently indicated for the symptomatic treatment of restless legs. The effect of pramipexole on sleep bruxism was investigated in subjects with ‘probable bruxism’ recruited at the Orofacial Pain Clinic.
Show More
loading
Actions
Is this you?
As a journalist, you can create a free Muck Rack account to customize your profile, list your contact preferences, and upload a portfolio of your best work.Get in touch with Jan
Contact Jan, search articles and posts on X, monitor coverage, and track replies from one place.
Learn more about Muck Rack