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Articles by Jan Klein
Prediction of Treatment Benefit With Internet-Based Cognitive Behavioral Therapy for Depression
Prediction of Treatment Benefit With Internet-Based Cognitive Behavioral Therapy for Depression Supplement 1. eMethods 1. Characteristics of Included Samples eMethods 2. Outcomes, Predictors, and Missing Data eMethods 3. Single and Multiple Imputation Procedures eMethods 4. Decision Accuracy Estimators: Definitions and Variance Formulas eFigure 1. Nested Cross-Validation Procedure eFigure 2. Distribution of Benefit Predictions by Model eFigure 3.
astral.ai.studio
astral.ai.studio August 15, 2026 Artificial intelligence is moving beyond chatbots, prompts, and isolated machine-learning models. The next phase is about building intelligent systems that can operate responsibly in the real world—systems that are useful, understandable, secure, adaptive, and designed around human needs. That is the vision behind astral.ai.studio, now online.
Aberrant insula activity to negative and reduced learning from positive feedback underlie maladaptive self-beliefs in depression
Abstract Maladaptive self-beliefs are a core symptom of major depressive disorder. These beliefs are perpetuated by a negatively biased integration of self-related feedback. Understanding the neurocomputational mechanisms of biased belief updating may help to counteract maladaptive beliefs and the maintenance of depression.
Ibrahim Ataman
İbrahim Ataman | Yazar İbrahim Ataman yazmaya geç başlamadı; yalnızca yazarlığını hayatının ilerleyen yıllarında görünür kıldı. Ibrahim Ataman Hakkında Hayatının büyük bölümünü, kelimelerin yalnızca düşünceleri değil, insanların hayatlarını da doğrudan etkilediği alanlarda geçirdi. Kararların, metinlerin ve cümlelerin somut sonuçlar doğurduğu bir dünyanın içinde yaşadığı için, yazmak uzun yıllar onun için bir ifade biçiminden çok bir sorumluluk anlamına geldi.
Shaping the future of endourology: role of education, simulation and uro-technology: a scoping review by the EAU Section of Endourology.
This scoping review synthesizes contemporary evidence on the role of simulation, uro-technology and structured training curricula in shaping the next generation of endourologists, both inside and outside of the operating theatre.
UAI (Understandable Ai)
UAI (Understandable Ai) The Next AI Revolution UAI Framework Transforms Black Box Intelligence into Transparent, Auditable, and Human Understandable Systems Jan Klein, 5 May 2026, Hannover, Germany - Contact: bix.pages.dev@gmail.com - ORCiD: 0009-0002-2951-995X Journal: Artificial intelligence - Repository: bix.pages.dev/UAI - PDF - Website: bix.pages.dev Keywords: UAI, Understandable AI, The Next Ai Revolution, Ai Revolution, Jan Klein, Explainable AI, XAI, Gemini, ChatGPT, LLaMA, Claude,...
Three Known Extensions of E=mc Simulations
Three Known Extensions of E=mc² Simulations The rest energy equation E = mc² represents a special case within a broader theoretical framework. When mass is in motion or embedded in external fields, the energy-momentum relation requires additional terms. This interactive visualization demonstrates three distinct extensions: 1.
VoiceScribe
VoiceScribe Live app: voice-scribe.netlify.app VoiceScribe is a realtime speech to text web app that supports 20 languages. You speak, it writes. Then you copy or share the text. It works on all browsers Chrome, Firefox, Safari, Edge, and mobile browsers. Simple. Your browser captures your voice. Google's AI turns it into text. You see it instantly. HTML structure of the page, language dropdown, buttons. CSS styling, responsive design, works on phone and desktop.
How to Mitigate the Effect of Observer Error When Unraveling Species‐Environment Associations? A Case Study With Tropical Tree Communities From Western Central Africa
1 Introduction Unraveling species–environment associations (SEA) remains a crucial task in community ecology (Sutherland et al. 2013) in order to understand how specific species or communities relate to different environmental factors such as soil, climate or human activity (see Bañares-de-Dios et al. 2022; Libalah et al. 2020; Vleminckx et al. 2020).
Digital intervention mylovia improves sexual functioning in women with sexual dysfunction in randomized controlled trial - npj Digital Medicine
Abstract Given the widespread issue of female sexual dysfunction and the scarcity of treatment options, novel therapeutic approaches are needed. This randomized controlled trial evaluated the use of mylovia©, a self-guided digital intervention for female sexual dysfunction and sexual pain disorder based on CBT and mindfulness, in addition to treatment as usual (TAU) compared to TAU plus information material. 252 women participated.
Understandable AI
Understandable AI The Next AI Revolution In today’s AI landscape, we are witnessing a paradox: as systems become more capable, they become less comprehensible. The current trajectory prioritizes raw power over transparency, leading to the Black Box era. Jan Klein is a key figure challenging this trajectory. His work at the intersection of architecture, standardization, and ethics advocates for a shift from systems that merely function to systems that can be intuitively understood.
Jan Klein | Understandable AI
The Architect of Understandable Artificial Intelligence In a time when Artificial Intelligence is rapidly increasing in capability, a countervailing challenge is growing just as fast: complexity. Systems are becoming more powerful, yet at the same time increasingly difficult to understand, even for their own developers. Jan Klein positions himself precisely at this critical point in technological evolution.
Planner App build with Google Ai Studio
This post is my submission for DEV Education Track: Build Apps with Google AI Studio. What I Built A Professional Digital Planner, Secure, Private, Saves all Your Notes, Media, and Events Directly on Your Device. No Cloud, No accounts, Just Your Data in Your Hands. Demo p3c.netlify.app My Experience While Google AI Studio was helpful in programming the app, it also made many errors and required a lot of patience to fix them manually.
Heterogeneity of Treatment Outcomes Across Therapists and Sites in a Randomized Multicentre Psychotherapy Trial
Summary This study highlights the importance of considering differences between treatment sites when evaluating psychotherapeutic treatments. This approach could make findings from psychotherapy studies more robust and, consequently, improve evidence-based mental healthcare. Specific characteristics of therapists and clinical sites that relate to treatment outcome are difficult to establish.
Addressing the Evolution of Cardenolide Formation in Iridoid-Synthesizing Plants: Site-Directed Mutagenesis of PRISEs (Progesterone-5β-Reductase/Iridoid Synthase-like Enzymes) of Plantago Species
All articles published by MDPI are made immediately available worldwide under an open access license. No special permission is required to reuse all or part of the article published by MDPI, including figures and tables. For articles published under an open access Creative Common CC BY license, any part of the article may be reused without permission provided that the original article is clearly cited. For more information, please refer to https://www.mdpi.com/openaccess.
Predicting the outcome of psychotherapy for chronic depression by person-specific symptom networks
Research ExplorerPublicationsPredicting the outcome of psychotherapy for chronic depressi... Abstract Bibliographical data
Implicaciones de la teoría de redes para el tratamiento de los trastornos mentales
La conceptualización de los trastornos mentales como entidades latentes ha sido cuestionada por la teoría de redes de los trastornos mentales, que afirma que los problemas psicológicos están constituidos por una red de síntomas que interactúan entre sí. Si bien se han discutido intensamente las implicaciones del enfoque de redes para la planificación y evaluación de tratamientos, falta apoyo empírico para las afirmaciones de la teoría de redes con respecto a los efectos del tratamiento.
Kompozycja szopkowa (2023): sinopsis, reparto y cartel
Ruboskizo S.L.·CIF B83121137·Calle de la Palma 7, 1B, 28008 Madrid (España) [email protected]·© 2026 Cines.com v2.121
Remote blended treatment for individuals with suicidal ideation: A single‐arm proof‐of‐concept trial
Key Practitioner Message A remote blended treatment combining videotherapy with self-help online modules might be a feasible approach to deliver specialized care for people with suicidal ideation. The remote treatment was highly acceptable and perceived as safe by patients and therapists. The next step is to conduct a randomized controlled feasibility trial to investigate safety and efficacy and to optimize the treatment design.
Implications of the Network Theory for the Treatment of Mental Disorders
Key Points Question To what extent do empirical data support specific hypotheses, derived from the network theory of mental disorders, regarding the (interindividual) changeability of symptom dynamics in response to treatment?
Utilization of Sludge from African Catfish (Clarias gariepinus) Recirculating Aquaculture Systems for Vermifiltration
This is an early access version, the complete PDF, HTML, and XML versions will be available soon.
The Optimal Input‐Independent Baseline for Binary Classification: The Dutch Draw
Abstract Before any binary classification model is taken into practice, it is important to validate its performance on a proper test set. Without a frame of reference given by a baseline method, it is impossible to determine if a score is ‘good’ or ‘bad’. The goal of this paper is to examine all baseline methods that are independent of feature values and determine which model is the ‘best’ and why.
Customer Experience: Conceptualization, Measurement, and Application in Omnichannel Environments
Customer Experience: Definition and Dimensions Definition Using the theory of the conscious mind as a theoretical foundation, we define CX as a customer’s subjective, directed, and multidimensional mental responses to an interaction with an experience partner at a touchpoint in a customer journey stage. These mental responses are subjectively valenced, so customers differentiate how positive their responses are for the different CX dimensions (De Keyser et al. 2020).
Future of robotic surgery in urology
Original Article Future of robotic surgery in urology Jens J. Rassweiler Corresponding Author E-mail address: jens.rassweiler@slk-kliniken.de http://orcid.org/0000-0002-0436-8246 Department of Urology, SLK‐Kliniken Heilbronn, University of Heidelberg, Heidelberg, Germany Correspondence: Jens J. Rassweiler, MD, Department of Urology, SLK‐Kliniken Heilbronn, Am Gesundbrunnen 20–26, 74078 Heilbronn, Germany.
Winter Welcome: Can a mouse cure the birthday blues?
Throughout history people have thought up creative reasons to explain what we had no hard facts to define. In this enlightened age, it is curious to me that the phenomenon occurs even though we have access to a vast amount of knowledge at our fingertips through technology. I present to readers my theory on “Birthday Blues.” As I've aged, I have discovered that I always seem sad around the time of my birthday in February.
Re: Update on Lasers in Urology. Current Assessment on Holmium:yttrium-aluminum-garnet (Ho:YAG) Laser Lithotripter Settings and Laser Fibers
By: Jens J. Rassweiler⁎ and Jan Klein European Urology, June 2016 Published online: 29 June 2016 Department of Urology, SLK Kliniken Heilbronn, Heilbronn, Germany ⁎ Corresponding author. Department of Urology, SLK Kliniken Heilbronn, Am Gesundbrunnen 20–24, 74076 Heilbronn, Germany. Article information PII: S0302-2838(16)30344-X DOI: 10.1016/j.eururo.2016.06.026© 2016 Published by Elsevier B.V.
The descent of the antibody-based immune system by gradual evolution
Immunologists classify immune responses into two categories: adaptive (acquired, anticipatory) immune system and innate immune system (1).
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