Jang Ryul Park on Muck Rack

Jang Ryul Park

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Articles

In vivo imaging of the hyaloid vascular regression and retinal and choroidal vascular development in rat eyes using optical coherence tomography angiography

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By Yongjoo Kim, Jang Ryul Park, Hye Kyoung Hong, Myounghee Han
| Nature Verified
Abstract This study investigates the hyaloid vascular regression and its relationship to the retinal and choroidal vascular developments using optical coherence tomography angiography (OCTA). Normal and oxygen-induced retinopathy (OIR) rat eyes at postnatal day 15, 18, 21, and 24 were longitudinally imaged using OCTA. At each day, two consecutive imaging for visualizing the hyaloid vasculature and the retinal and choroidal vasculatures were conducted.
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Tie2 activation promotes choriocapillary regeneration for alleviating neovascular age-related macular degeneration

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By Intae Park, Jaeryung Kim, Jang Ryul Park, Jeongwoon Choi
| Science Magazine Verified
Abstract Choriocapillary loss is a major cause of neovascular age-related macular degeneration (NV-AMD). Although vascular endothelial growth factor (VEGF) blockade for NV-AMD has shown beneficial outcomes, unmet medical needs for patients refractory or tachyphylactic to anti-VEGF therapy exist. In addition, the treatment could exacerbate choriocapillary rarefaction, necessitating advanced treatment for fundamental recovery from NV-AMD.
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