Janka Zsófia Csepregi

Introduction Genetically manipulated mice lacking a certain hematopoietic lineage (1–11) have strongly contributed to our understanding of immune and inflammatory processes in health and disease. The best example is the deficiency of the recombination activating genes Rag1 or Rag2, which lack B and T lymphocytes and, therefore, are widely used to test the role of the adaptive immune response in in vivo biological processes (1).

Myeloid-Specific Deletion of Mcl-1 Yields Severely Neutropenic Mice That Survive and Breed in Homozygous Form Janka Zsófia Csepregi, Anita Orosz, Erik Zajta, Orsolya Kása, Tamás Németh, Edina Simon, Szabina Fodor, Katalin Csonka, Balázs L. Barátki, Dorottya Kövesdi, You-Wen He, Attila Gácser, Attila Mócsai The Journal of Immunology November 21, 2018, ji1701803; DOI: 10.4049/jimmunol.1701803