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Jarkko P. Hytönen on Muck Rack

Jarkko P. Hytönen

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Articles

Low and High Pressor Doses of Ang II Lead to Two Distinct Phenotypes of Hypertensive Heart Disease in Mice

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By Tuisku Suoranta, Jarkko P. Hytönen, Diana Törmä, Mimmi Rinta-Harri
| Wiley Online Library Verified
1 Introduction Cardiovascular diseases (CVD) are still the leading cause of morbidity, disability, and mortality worldwide [1], with hypertension being a dominant cause for their development [2]. The dysregulation of the renin-angiotensin-aldosterone system (RAAS) leads to elevated angiotensin II (Ang II) and aldosterone levels, promoting vasoconstriction and sodium retention, and thereby hypertension.
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