Jatupoom Chansomboon

1 Introduction The management of traumatic limb-threatening injuries has evolved over the past four decades, with free flap reconstruction becoming a common approach for complex extremity defects. The pioneering work of Byrd, Godina, and Lister et al. established progressively earlier reconstruction timing (within 5 days, 72 h, and 24 h, respectively), with demonstration of favorable clinical outcomes (Byrd et al. 1985, 1981; Godina and Lister 1986; Breidenbach 1989).