1 INTRODUCTION Cardiovascular disease (CVD) has been recognized as the commonest cause of erectile dysfunction (ED), whose importance as a sentinel symptom has grown.1 Both share a similar endothelial dysfunction pathophysiology related to age,2, 3 hypertension, smoking, or diabetes.4, 5 Different studies have found that patients with moderate or severe impairments of ejection fraction had significantly increased ED.6, 7 Thus, identification of the biomarkers that could accurately predict...