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Javiera Aranda on Muck Rack

Javiera Aranda

As seen in: Nature
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Articles

Intermittent time-restricted feeding improves physical performance and modulates mitochondrial morphology in a muscle fiber type dependent manner in middle-aged mice

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By Francisco Diaz-Castro, Juan Carlos Bórquez, Luis Videla, Carla Basualto-Alarcón, Franco Tacchi, Marianny Portal-Rodriguez, Rodrigo Troncoso, Andrea del Campo, Fernanda Briones-Manríquez, Gonzalo Almarza, Bastián Ramos, María José Silva-Urbina, Luciana Pesce, Valentina Jeria, Javiera Aranda, Amanda Grau-Grass, Claudio Cabello-Verrugio
| Nature Verified
Abstract Sarcopenia, defined as the age-related decline in skeletal muscle mass and function, markedly reduces physical performance, threatens functional independence, and diminishes quality of life in older adults. Although the clinical manifestations of sarcopenia typically emerge later in life, underlying molecular alterations, particularly within the mitochondrial network, occur well before symptom onset.
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