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Jay P. Barbor on Muck Rack

Jay P. Barbor

As seen in: ACS Publications
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Articles

Formation of All-Carbon Quaternary Centers via Enantioselective Pd-Catalyzed α-Vinylation of γ-Lactams

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By Melinda Chan, Carina Jette, Farbod A. Moghadam, Jay P. Barbor
| ACS Publications
γ-Lactams are ubiquitous heterocyclic motifs found in pharmaceuticals and natural products alike (Figure 1). (1) Despite this, the direct vinylation of these and other (2) scaffolds largely remains an unsolved problem in organic synthesis, which limits the feasibility of convenient disconnections in the synthesis of complex scaffolds with potential biological applications.
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Formation of All-Carbon Quaternary Centers via Enantioselective Pd-Catalyzed α-Vinylation of γ-Lactams

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By Farbod A. Moghadam, Jay P. Barbor, Melinda Chan, Carina Jette
| dx.doi.org
γ-Lactams are ubiquitous heterocyclic motifs found in pharmaceuticals and natural products alike (Figure 1). (1) Despite this, the direct vinylation of these and other (2) scaffolds largely remains an unsolved problem in organic synthesis, which limits the feasibility of convenient disconnections in the synthesis of complex scaffolds with potential biological applications.
Open in Who Shared Issue with article?
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