Jayashree Suresh Ladke on Muck Rack

Jayashree Suresh Ladke

As seen in: BioRxiv
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Articles

Interaction with IP6K1 supports pyrophosphorylation of substrate proteins by the inositol pyrophosphate 5-IP7

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By Aisha Hamid, Jayashree Suresh Ladke, Akruti Shah, Monisita Pal
| BioRxiv
Abstract Inositol pyrophosphates (PP-IPs) are a sub-family of water soluble inositol phosphates that possess one or more diphosphate groups. PP-IPs can transfer their β-phosphate group to a phosphorylated Ser residue to generate pyrophosphorylated Ser. This unique post-translational modification occurs on Ser residues that lie in acidic stretches within an intrinsically disordered protein sequence.
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