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Jaylah C. Captain

As seen in: Nature
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Articles

Berry-derived gold nanoparticles induce integrated ROS-mediated apoptosis, immune modulation, and transcriptomic remodeling in 4T1 triple-negative cancer cells

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By Oladapo F. Fagbohun, Chengyu Gao, Babatunde Olawoye, Rachel Berry, Randy Harris, Amanda Rollins, Jitcy S. Joseph, Olatomide A. Fadare, Russell Kincaid, Adewale O. Oladipo, Jaylah C. Captain, Olive Iragena, Xavier McDougle
| Nature Verified
Abstract Comprehensive molecular and phenotypic characterization of tumor models is still needed for a robust understanding of breast cancer mechanisms and therapies. Here, we explore the genome, transcriptome, and proteome of treated and untreated 4T1 triple-negative breast cancer cells to integrate genomic vulnerabilities and mutational profiling with novel treatment-induced delivery, signaling, and apoptotic responses.
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