Jee Young Sung on Muck Rack

Jee Young Sung

As seen in: Nature
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Articles

Syndesmos functions as a tumor suppressor by facilitating epithelial cell adhesion mediated by interactions of E-cadherin and β-catenin

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By Jisun Hwang, Bohee Jang, Hyewon Shim, Hyeryun Kwon, Eun Kyung Hong, Eek-hoon Jho, Ga-Eun Lim, Jee Young Sung, Yong-Nyun Kim, Eok-Soo Oh
| Nature
Abstract Syndesmos (SDOS), which regulates cytoskeletal organization via interaction with syndecan-4 in fibroblasts, was under-expressed in highly metastatic HCT116 colon cancer cells compared to weakly metastatic HT29 cells. SDOS overexpression decreased migration and proliferation of HCT116 cells, while siRNA-mediated knockdown of SDOS increased these activities in HT29 cells.
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