The U.S. and Israel have launched strikes against Iran after weeks of talks bore no resolution on Iran’s nuclear program. The strikes are implicitly aimed at attempting to change Iran’s regime, as U.S. president Donald Trump urged Iranians to “take over [their] government.” U.S. attacks were reported in the capital Tehran as well as major cities Isfahan, Shiraz, and Tabriz. Further attacks occurred around Iranian oil-refining infrastructure near the Persian Gulf. At least 40 people have died.