Jeffrey Jay Moffat on Muck Rack

Jeffrey Jay Moffat

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Articles

How Chemokine CCL28 Binds to Yersinia pseudotuberculosis

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By Jeffrey Jay Moffat, David Erickson, Brigham Young
| scholarsarchive.byu.edu
Keywords chemokine CCL28, Yersinia pseudotuberculosis, binding Department Microbiology and Molecular Biology Abstract Chemokines are tiny proteins that play a valuable role in defending our bodies against bacteria and other pathogens. Chemokines are best known for their role in attracting immune cells to areas of infection.
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Arid1b haploinsufficiency disrupts cortical interneuron development and mouse behavior

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By Eui-Man Jung, Jeffrey Jay Moffat, Jinxu Liu, Shashank Manohar Dravid
| Nature Verified
Haploinsufficiency of the AT-rich interactive domain 1B (ARID1B) gene causes autism spectrum disorder and intellectual disability; however, the neurobiological basis for this is unknown. Here we generated Arid1b-knockout mice and examined heterozygotes to model human patients. Arid1b-heterozygous mice showed a decreased number of cortical GABAergic interneurons and reduced proliferation of interneuron progenitors in the ganglionic eminence.
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