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ICU Clinicians' View on Platelet Transfusion Thresholds for a Future Trial—Protocol for an International Survey
J. A.Barakji, C. T.Anthon, A.Granholm, M. H.Møller, J.Stensballe, and A.Perner, “ICU Clinicians' View on Platelet Transfusion Thresholds for a Future Trial—Protocol for an International Survey,” Acta Anaesthesiologica Scandinavica70, no. 6 (2026): e70263, https://doi.org/10.1111/aas.70263. Conflicts of Interest All authors are involved in designing the future INCEPT-Platelets domain within the Intensive Care Platform Trial (INCEPT; www.incept.dk), which investigates platelet transfusion strategies.
Cannabinoids versus placebo for pain: A systematic review with meta-analysis and Trial Sequential Analysis
Primary outcomes All-cause mortality. Seven trials randomising 2073 participants reported on all-cause mortality. Meta-analysis showed no evidence of a difference between cannabinoids versus placebo (RR 1.20; 98% CI 0.85 to 1.67; P = 0.22; low certainty of evidence; S1 Fig in S1 File). Visual inspection of the forest plot, I2-statistic (I2 = 7%), and tau2 statistic (τ2 = 0.01; τ = 0.1) indicated low heterogeneity.
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