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Jehan Zeb Khan

As seen in: Nature, Wiley Online Library, PLOS ONE
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Articles

1,3,4 oxadiazole derivative attenuates neurotransmitter-mediated inflammatory response in EAE model of multiple sclerosis

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By Syeda Zainab, Jehan Zeb Khan, Humaira Nadeem, Muhammad Khalid Tipu, Nadeem Ahmad, Zaheer Ul-haq, Ihsan ul Haq, Nadeem Irshad
| Nature Verified
Abstract Multiple sclerosis (MS) has a complex pathophysiology, comprising inflammation, demyelination, and alterations in neurotransmitter levels. Dysregulation of neurotransmitters, an imbalance between GABAergic and glutamatergic activity, enhanced oxidative stress, and an inflammatory response have all been involved in the disease. These mechanisms play a crucial role in regulating neuronal plasticity and activity.
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In Silico molecular docking and molecular dynamic simulation of transferrin coated Phenytoin loaded SLNs with molecular targets of epilepsy

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By Islamabad Pakistan, Hussain Ali, Jehan Zeb Khan, Ahmad Zeb
| PLOS ONE
Loading metrics Open Access Peer-reviewed Research Article Citation: Zeb A, Ali H, Khan JZ, Shah FA, Alattar A, Alanazi FE (2025) In Silico molecular docking and molecular dynamic simulation of transferrin coated Phenytoin loaded SLNs with molecular targets of epilepsy. PLoS One 20(6): e0325772.
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Effect of Bacillus clausii in attenuating symptoms of DSS‐induced ulcerative colitis by modulating NFkB pathway and oxidative stress in mice

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By Syeda Zainab, Mujeeb Ur Rehman, Fawad Ali Shah, Jehan Zeb Khan
| Wiley Online Library Verified
CONFLICT OF INTEREST STATEMENT The authors declare no conflicts of interest. REFERENCES 1, , , et al. Bortezomib protects against dextran sulfate sodium-induced ulcerative colitis in mice. Mol Med Rep. 2017; 15(6): 4093-4099. 2, , , . Global, regional and national burden of inflammatory bowel disease in 204 countries and territories from 1990 to 2019: a systematic analysis based on the global burden of disease study 2019. BMJ Open. 2023; 13(3):e065186. 3, .
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