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Jennifer Barrat on Muck Rack

Jennifer Barrat

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Articles

Evolutionary conservation analysis reveals a primordial function of STING as a regulator of lipid metabolism via FADS2

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By Soumyabrata Guha, Joanna Re, Morgane Chemarin, Adeline Augereau, Yasmine Messaoud-Nacer, Hanane Chamma, Jenny Nguyen, Arielle Woznica, Niyazi Acar, Isabelle K. Vila, Pierre Boudinot, Nadine Laguette, Stéphane Grégoire, Pierre Le Hars, Victoria Bergas, Collin McNairy, Jennifer Barrat
| Nature Verified
Abstract The stimulator of interferon genes (STING) is a pivotal regulator of type I interferon (IFN) responses. Although the IFN system is confined to vertebrates, STING is present across metazoans and in some unicellular eukaryotes, suggesting involvement in distinct functions prior to vertebrate divergence. Here we explore the conservation of STING-mediated regulation of polyunsaturated fatty acid (PUFA) metabolism.
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