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Structure-Guided Discovery of a Cold-Responsive Antifreeze-Like Protein from Antarctic Flavobacterium sp. PL002

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By Hui Fan, Hackwon Do, Jennifer Charles Labo
| preprints.org
Antarctic microorganisms experience persistent subzero temperatures and repeated freeze–thaw cycles that require specialized mechanisms for survival. Although transcriptomic studies have identified numerous cold-responsive genes, many remain annotated as hypothetical proteins with unknown functions. In this study, we investigated PL002-1792, a strongly upregulated hypothetical protein from Antarctic Flavobacterium sp.
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