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Jennifer L. Barnas on Muck Rack

Jennifer L. Barnas

As seen in: Science Magazine, The Journal of Immunology
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Articles

A population-scale transcriptional atlas of blood and tissue in lupus nephritis

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By Shreya Kashyap, Alan Chramiec, M. Silva, Nicholas W. Sugiarto, Siddarth Gurajala, Michelle Curtis, Thomas Eisenhaure, Arnon Arazi, Andrea Fava, Qian Xiao, Joseph R. Mears, Brad H Rovin, Celine C. Berthier, Yu Zhe Zhao, Peter Izmirly, Jennifer L. Barnas, Paul Hoover, Michael Peters, Raktima Raychowdhury, Alice Horisberger, Saori Sakaue, Richard A. Furie, H. Michael Belmont, David A Hildeman, E. Steve Woodle
| Science Magazine Verified
Editor’s summary Abstract Supplementary Materials REFERENCES AND NOTES Information & Authors Metrics & Citations Check Access References Figures Tables Media Share Editor’s summary Lupus nephritis (LN) is a severe form of lupus that damages the kidneys. Here, Sugiarto et al. created a single-cell and single-nuclear atlas of kidney biopsy tissues and blood samples from individuals with LN.
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B Cell Activation and Plasma Cell Differentiation Are Promoted by IFN-λ in Systemic Lupus Erythematosus

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By Jennifer L. Barnas, Jennifer S. Albrecht, Nida Meednu, Diana F. Alzamareh
| The Journal of Immunology Verified
Jennifer L. Barnas, Jennifer Albrecht, Nida Meednu, Diana F. Alzamareh, Cameron Baker, Andrew McDavid, R. John Looney and Jennifer H. Anolik J Immunol December 1, 2021, 207 (11) 2660-2672; DOI: https://doi.org/10.4049/jimmunol.2100339 Key Points A type I IFN transcriptional profile is upregulated in SLE B cells. Human B cells express type I IFN genes in response to IFN-λ (type III IFN). IFN-λ may enhance TLR7-mediated B cell activation and PC differentiation in SLE.
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B Cell Activation and Plasma Cell Differentiation Are Promoted by IFN-λ in Systemic Lupus Erythematosus

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By Jennifer S. Albrecht, Nida Meednu, Jennifer L. Barnas, Diana F. Alzamareh
| The Journal of Immunology Verified
Jennifer L. Barnas, Jennifer Albrecht, Nida Meednu, Diana F. Alzamareh, Cameron Baker, Andrew McDavid, R. John Looney and Jennifer H. Anolik J Immunol October 27, 2021, ji2100339; DOI: https://doi.org/10.4049/jimmunol.2100339 Key Points A type I IFN transcriptional profile is upregulated in SLE B cells. Human B cells express type I IFN genes in response to IFN-λ (type III IFN). IFN-λ may enhance TLR7-mediated B cell activation and PC differentiation in SLE.
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