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Articles

AMPK Regulates Phagophore-to-Autophagosome Maturation

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By Jens Christopher Schmidt, Carlo Barnaba, David G Broadbent, Gloria Perez
| biorxiv.org
Abstract Autophagy is an important metabolic pathway that can non-selectively recycle cellular material or lead to targeted degradation of protein aggregates or damaged organelles. Autophagosome formation starts with autophagy factors accumulating on lipid vesicles containing ATG9. These phagophores attach to donor membranes, expand via ATG2-mediated lipid transfer, capture cargo, and mature into autophagosomes, ultimately fusing with lysosomes for their degradation.
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Single-molecule imaging reveals the kinetics of non-homologous end-joining in living cells

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By Mariia Mikhova, Joshua R Heyza, Katheryn Meek, Jens Christopher Schmidt
| biorxiv.org
Thank you for your interest in spreading the word about bioRxiv. NOTE: Your email address is requested solely to identify you as the sender of this article. Your Email * Your Name * Send To * Enter multiple addresses on separate lines or separate them with commas. Message Subject (Your Name) has forwarded a page to you from bioRxiv Message Body (Your Name) thought you would like to see this page from the bioRxiv website.
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