Jérome Baranger

Abstract Neuropathic pain results from damage to the nervous system and causes persistent changes in brain function that contribute to chronic pain. Understanding how these changes evolve over time is essential for identifying the mechanisms that sustain the disease. Here we show how brain-wide communication changes during the development and persistence of neuropathic pain in male mice using resting-state functional ultrasound imaging in awake and anesthetized animals.

Abstract Adolescent idiopathic scoliosis (AIS) is the most prevalent pediatric spine disorder, developing in the absence of obvious physiological defects. Genome sequencing and functional studies have demonstrated association of musculoskeletal collagen variants and cartilaginous extracellular matrix (ECM) defects in a subset of patients. However, the underlying biological causes of AIS remain poorly understood, limiting treatment options.

Abstract Recent studies have shown growing evidence that brain function is closely synchronised with global physiological parameters. Heart rate is linked to various cognitive processes and previous research has also demonstrated a strong correlation between neuronal activity and breathing. These findings highlight the significance of monitoring these key physiological parameters during neuroimaging as they provide valuable insights into the overall brain function.