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Development and validation of a pharmacogenomics reporting workflow based on the Illumina Global Screening Array chip

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By Pamela Gan, Mazaya Yumna, Jessline Haruman, Husnul Khotimah Matoha
| biorxiv.org
Abstract Background: Microarrays are a well-established and widely adopted technology capable of interrogating hundreds of thousands of loci across the human genome. Combined with imputation to cover common variants not included in the chip design, they offer a cost-effective solution for large-scale genetic studies. Beyond research applications, this technology can be applied for testing pharmacogenomics, nutrigenetics, and complex disease risk prediction.
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