Jeungchan Lee

Objective Fibromyalgia (FM) is characterized by pervasive pain-related symptomatology and high levels of negative affect. Mind–body treatments such as cognitive behavioral therapy (CBT) appear to foster improvement in FM via reductions in pain-related catastrophizing, a set of negative, pain-amplifying cognitive and emotional processes. However, the neural underpinnings of CBT's catastrophizing-reducing effects remain uncertain.

ORIGINAL ARTICLE Jeungchan Lee, Corresponding Author jlee196@mgh.harvard.edu Department of Radiology, Athinoula A. Martinos Center for Biomedical Imaging, Massachusetts General Hospital, Harvard Medical School, Charlestown, MA, 02129 USA Corresponding author Jeungchan Lee, PhD, Martinos Center for Biomedical Imaging, 149 Thirteenth Street, Suite 2301, Charlestown, MA 02129. Telephone number: +1-617-724-3402 E-mail address: jlee196@mgh.harvard.edu Search for more papers by this author Ovidiu C.

Introduction Migraine is an episodic, recurrent dysfunction of brain excitability that is characterized by attacks of moderate or severe unilateral throbbing and pulsating headaches (Noseda and Burstein, 2013). The most characteristic symptoms associated with migraine include photophobia, phonophobia, cutaneous allodynia, and gastrointestinal symptoms (Dodick, 2018a).