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Jeyrroy Gabriel on Muck Rack

Jeyrroy Gabriel

As seen in: Nature
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Articles

Single-cell analysis of psoriasis resolution demonstrates an inflammatory fibroblast state targeted by IL-23 blockade - Nature Communications

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By Francesca Capon, Luc Francis, Treasa Jiang, Jeyrroy Gabriel
| Nature Verified
Abstract Biologic therapies targeting the IL-23/IL-17 axis have transformed the treatment of psoriasis. However, the early mechanisms of action of these drugs remain poorly understood. Here, we perform longitudinal single-cell RNA-sequencing in affected individuals receiving IL-23 inhibitor therapy.
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