Jiachen Cui on Muck Rack

Jiachen Cui

As seen in: Nature
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Articles

Targeting ZMIZ1 induces differentiation in acute myeloid leukemia via chromatin remodeling

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By Huimin Li, Yabin Liu, Ziyu Fu, Yiyang Xu, Sizhe Yang, Kai Zhu, Yuhao Xue, Yi Zhang, Yiheng Zhao, Guiqiyang Xiang, Xiaoguang Xu, Shuting Yu, Qiang Wang, Yuting Dai, Qianqian Zhang, Jianfeng Li, Ruihong Zhang, Fangyi Dong, Shengyue Wang, Saijuan Chen, Bo Jiao, Shuo Chen, Yun Tan, Jiachen Cui, Fulun Jiao, Shanhe Yu
| Nature
Abstract Acute myeloid leukemia (AML) is an aggressive hematologic malignancy characterized by profound transcriptional dysregulation and impaired hematopoietic differentiation. While differentiation therapy has revolutionized treatment in acute promyelocytic leukemia (APL), analogous strategies in non-APL AML remain elusive.
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