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Jiamo Zhang on Muck Rack

Jiamo Zhang

As seen in: Nature, Frontiers
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Articles

Liquid biopsy-guided kidney-sparing management in upper tract urothelial carcinoma: from preoperative risk stratification to perioperative surveillance

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By Jiarun Tang, Yu ZHANG, Ke Hu, Jing Qing, Jiamo Zhang, Difei Yu
| Frontiers
Abstract Upper tract urothelial carcinoma (UTUC) presents a clinically important gap in urologic oncology: treatment intensity is determined before surgery, yet conventional preoperative risk stratification remains imperfect. Kidney-sparing surgery (KSS) is established for selected low-risk disease and is increasingly considered when renal preservation is clinically important, but safe selection depends on distinguishing technically manageable tumors from biologically unsuitable disease.
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Candida auris vacuolar calcium pump mediates fluconazole efflux and resistance evolution - Nature Microbiology

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By Yabing Song, Jinxin Chen, Junhua Wan, Jiamo Zhang, Qizheng Liu, Fei Sun, Hanlin Zhang, Yuru Guo, Yali Chen, Ziyu Yan, Jianbin Wang, Kun Chen, YUE WANG, Jiaxin Gao, Eve W. L. Chow
| Nature Verified
Abstract Candida auris is an emerging fungal pathogen notable for its intrinsically high resistance to fluconazole, the most prescribed antifungal drug. However, the genetic regulators underlying fluconazole susceptibility in C. auris remain unclear. Here we performed a pooled screen of piggyBac (PB) transposition mutants and identified significant enrichment of mitochondrial genes whose inactivation reduces fluconazole susceptibility.
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