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Articles by Jianjun Han
Metformin and atorvastatin ameliorate MASH via the AMPK/NF-κB pathway
Abstract Background: Despite being a globally prevalent chronic liver disease, MASLD currently lacks any approved pharmacotherapy. MET and ATO individually confer benefits against MASLD, but their combined therapeutic effects have seldom been investigated. The current work aimed to verify the therapeutic benefits of their combined intervention on MASH. Methods: A MASH-like mouse model was established via HFD feeding combined with CCl4 injection, alongside an FFA-induced HepG2 steatosis model.
AI in predicting the macrotrabecular-massive subtype of HCC and informing treatment selection: a multi-center and prospective validation study
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Abstract The macrotrabecular-massive (MTM) subtype of hepatocellular carcinoma (HCC) is associated with aggressive biology and poor prognosis. We aimed to develop a CT-based artificial intelligence model (DeepCT-MTM) for the noninvasive prediction of MTM-HCC and investigate its prognostic utilities as well as biological underpinnings. A total of 3118 patients with HCC were included from 20 tertiary-care hospitals.
By Ran Wei, Hanyu Jiang, Mengxuan Zuo, Xuelei He, Fei Cao, Shaolong Li, Wang Li, Wendao Liu, Chengzhi Li, Xin Li Verified, Jianjun Han, Dong Yan, Weiling He, Feng Duan, Xinya Zhao
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Nature
Verified
Structure, spectroscopic properties and optical temperature sensing behavior of glass-ceramics containing polymorphic CaTa2O6: Er3+/Yb3+ nanocrystals
Structure, spectroscopic properties and optical temperature sensing behavior of glass-ceramics containing polymorphic CaTa2O6: Er3+/Yb3+ nanocrystals Novel glass-ceramics (GCs) containing polymorphic CaTa2O6: Er3+/Yb3+ nanocrystals are prepared by aerodynamic levitation method following with a heat-treatment of the precursor glasses (PG). Phase transition from cubic to orthorhombic crystal forms depending on the heat-treatment temperature is observed.
Circ_0001982 aggravates breast cancer development through the circ_0001982‐miR‐144‐3p‐GSE1 axis
CONFLICT OF INTEREST STATEMENT The authors declare no conflict of interest. Supporting Information Filename Description jbt23565-sup-0001-Language_editing_certificate.pdf95.5 KB Supporting information. REFERENCES 1, , , , , , , Ann. Biol. Clin. 2016, 74, 653. 2, Adv. Exp. Med. Biol. 2019, 1152, 51. 3, , , , , , , , , Hum. Reprod. 2017, 32, 1033. 4, , Acta Oncol. 2011, 50, 187. 5, , , , Biochem. Cell Biol. 2021, 99, 277. 6, Nat. Rev. Mol. Cell Biol. 2016, 17, 205. 7, Adv. Exp. Med. Biol. 2018, 1087, 67.
Spatiotemporal Patterns of Ammonia Nitrogen and Chemical Oxygen Demand in the Huaihe River-Hongze Lake System (Eastern China)
Abstract : Understanding variations in contaminant concentrations and exploring their driving factors are essential for pollution control and water environment improvement. The Huaihe River Basin, as an important region in the eastern region of China, has attracted much attention to its water environment issues in recent years.
Thieme E-Journals - Synfacts
Synfacts 2023; 19(01): 0029 DOI: 10.1055/s-0042-1751795 Synthesis of Materials and Unnatural Products Key words phosphaalkenes - [2+2] cycloaddition - tetraaryl ethene - diaryl ketones Publication History Article published online: 16 December 2022 Georg Thieme Verlag KG Rüdigerstraße 14, 70469 Stuttgart, Germany
Intense up-conversion emission from Er3+/Yb3+ ions co-doped transparent oxyfluoride glass-ceramics containing Y5O4F7 nanorods for optical thermometry
Intense up-conversion emission from Er3+/Yb3+ ions co-doped transparent oxyfluoride glass-ceramics containing Y5O4F7 nanorods for optical thermometry Er3+/Yb3+ ions co-doped transparent glass-ceramics containing Y5O4F7 nanorods were prepared through conventional melt-quenching and subsequent heat-treatment method.
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