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Design, Synthesis, and Antihematological Tumor Activity of Dihydroartemisinin-Loxoprofen Hybrids
Conflict of Interest The authors declare no conflict of interest. Data Availability Statement The data that support the findings of this study are available from the corresponding author upon reasonable request. Supporting Information Filename Description cmdc70095-sup-0001-SuppData-S1.pdf2.9 MB Supplementary Material References 1, , , Br. J. Pharmacol. 2025, 182, 2094. 2, , , , , , Br. J. Pharmacol. 2025, 182, 2235. 3, , , , , , , , , Br. J. Pharmacol. 2025, 182, 2287. 4, , , , , Microbiol. Res.
Bearing Digital Twin Based on Response Model and Reinforcement Learning
1. Introduction Rolling element bearings serve as critical components within rotating machinery, exerting significant influence over the overall performance of the machine. Modeling techniques are commonly employed to simulate the dynamic behavior of the bearings. Technically, mechanism-based and signal-based methods find extensive application for simulating the vibration response of rolling element bearings under both normal and fault operating conditions [1,2].
Front Cover: Design, Synthesis, and Antitumor Activities of Isomers of Artemisinin Dimer Derivatives (Chem. Biodiversity 7/2023)
Graphical Abstract Front Cover. Artemisinin is extracted from Artemisia annua L. Its derivative, dihydroartemisinin (DHA), is divided into α and β configuration based on the orientation of hydroxy groups on the 10th carbon. Starting from DHA as the raw material, modifications of the C-10 position were made, and artemisinin dimer derivatives with varying chiral structures were synthesized by linking different motifs.
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