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As a journalist, you can create a free Muck Rack account to customize your profile, list your contact preferences, and upload a portfolio of your best work.Articles
Immune checkpoint inhibition in bone metastases: lesion response heterogeneity, the osteoimmune niche, and microenvironment-directed therapy
Abstract Bone metastases are common in advanced solid tumors and are clinically important not only because they cause skeletal-related events, including bone pain, pathological fractures, and spinal cord compression, but also because they may influence responses to immune checkpoint inhibitors (ICIs). Clinical evidence has consistently associated bone metastases with poorer survival after ICI treatment.
Multiphysics finite element analysis of vertebral stability in simulated osteolytic lumbar defects treated with 125 I brachytherapy and vertebroplasty
Abstract Objective: This study evaluates the impact of radiation dose, thermal effects, and mechanical factors on vertebral stability and safety in a finite element model of simulated osteolytic defects and compared 125I seed brachytherapy alone with 125I brachytherapy combined with percutaneous vertebroplasty (PVP). Methods: A 3D FE model of the L3–L5 lumbar spine was reconstructed from CT data of a healthy adult subject.
Interactions with educational chatbots: the impact of induced emotions and students’ learning motivation
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