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Jiasong Guo on Muck Rack

Jiasong Guo

As seen in: Nature
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Articles

RhoA in postnatal spinal motoneuron is essential for peripheral myelination

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By Shuyi Xu, Ying Zou, Mengyao Zhao, Jiale Cai, Xinrui Ma, Xianghai Wang, Anbo Zhang, Jiasong Guo
| Nature Verified
Abstract Peripheral myelination requires precise axon-glia communication, yet the neuronal intrinsic machinery that governs the release of axonal signals remains incompletely understood. Here, we discover that RhoA, a classic cytoskeletal regulator, is highly expressed in postnatal spinal motoneurons and unexpectedly governs this axon-glia communication.
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