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Combination of Tanshinone IIA and Matrine Alleviates Lipopolysaccharide‐Induced Acute Lung Injury by Supressing Ferroptosis via Nrf2/HO‐1 Pathway Activation
Conflicts of Interest The authors declare no conflicts of interest. Supporting Information Filename Description cep70072-sup-0001-FigureS1.tifTIFF image, 849.6 KB Figure S1: Using CompuSy software to verify the synergistic effect of Tanshinone IIA (TIIA) and Matrine (MAT). Chou-Talalay was used to analyse the synergistic relationship between TIIA and MAT. CI > 1 represents antagonistic effect, CI = 1 represents additive effect and CI < 1 represents synergistic effect.
Drug repositioning for pan-cancers of the digestive system: Identification of amonafide and BX795 as potential therapeutics via integrative Omics analysis
Loading metrics Open Access Peer-reviewed Research Article Citation: Liu W, Gao J, Ren S, Nashun B, Gao F (2025) Drug repositioning for pan-cancers of the digestive system: Identification of amonafide and BX795 as potential therapeutics via integrative Omics analysis. PLoS One 20(6): e0325700. https://doi.org/10.1371/journal.pone.0325700 Editor: Xinjun Lu,, Sun Yat-Sen University, CHINA Received: February 10, 2025; Accepted: May 15, 2025; Published: June 16, 2025 Copyright: © 2025 Liu et al.
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