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Jiaying Wu on Muck Rack

Jiaying Wu

As seen in: Emerging Infectious Diseases Journal, Nature, Wiley, Wiley Online Library, arXiv, Frontiers, MDPI, Taylor & Francis Online, Virology Journal, Science Magazine and
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Articles

Synergistic anticancer effect of brusatol combined with paclitaxel on HCT116 cells with preliminary evidence implicating the hsa-miR-29c-3p/CDC42/p53 axis

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By Zixuan Hu, Jiaying Wu, Wei Ren, Dane Huang, Nan Yao, Caifu Fang
| Nature Verified
Abstract Colorectal cancer (CRC) is a common and life-threatening malignant tumor with a high mortality rate. Paclitaxel is a commonly used chemotherapy drug. Brusatol, a primary chemical component isolated from Brucea javanica, has been reported to significantly inhibit the proliferation of various cancer cell lines. Network pharmacology was employed to predict the core targets and signaling pathways of brusatol against colorectal cancer.
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Sub1 contributes to heart failure with preserved ejection fraction driven by aging in mice

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By Di Zhao, Ling Lin, Yufei Zhou, Jiaying Wu, Ran Xu, Linnan Li, Xiaoxue Zhang, Hong Lin, Jienan Wang, Zhiwen Ding, Pan Gao, Jian Wu, Yunzeng Zou, Kunming Dai
| Nature Verified
Abstract Heart failure with preserved ejection fraction (HFpEF) accounts for approximately half of all heart failure cases and predominantly affects older individuals, yet effective treatments remain limited. The molecular mechanisms linking cardiac aging to HFpEF are not fully understood. Here we show that the transcriptional regulator Sub1 is upregulated in aged hearts and in mouse models of HFpEF.
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Ultrafast charge-generation dynamics through interfacial energetic modulation for high-performance single-component organic photovoltaics with 14.8% efficiency

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By Yao Li, Yongmin Luo, Yulong Hai, Xinkang Wang, Lunbi Wu, Ruijie Ma, Kezhou Fan, Sha Liu, Tao Jia, Junwu Chen, Jiaying Wu
| Nature Verified
Abstract Bulk heterojunction (BHJ) organic solar cells (OSCs) have achieved high efficiencies but suffer from poor morphological stability due to phase separation after long-term operation. Single-component OSCs (SCOSCs) based on double-cable polymers (DCP), offer improved stability through covalently linked donor and acceptor units. However, their efficiency remains limited by inefficient charge generation arising from extensive intermixed morphologies.
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