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Jicang Wang on Muck Rack

Jicang Wang

As seen in: Frontiers, Pakistan Journal of Zoology
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Articles

The role of endoplasmic reticulum stress-mediated autophagy in cadmium-induced liver injury in rats

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By Chengxiang Guo, Junbing Mao, Jiale Dong, Cai Zhang, YUE WANG, Shuai Wang, Shuai Guo, Jicang Wang
| Frontiers
Abstract Cadmium (Cd) is a widespread toxicant with high bioaccumulation potential. This study explores the interplay of endoplasmic reticulum stress (ERS), autophagy, and apoptosis in Cd-induced hepatotoxicity, focusing on whether ERS-driven autophagy protects against liver injury. Male SD rats (4 weeks old, n = 24) were acclimatized for 7 days and randomized into four groups receiving CdCl₂ at doses of 0, 0.5, 1, or 2 mg/kg for 14 consecutive days.
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