Jihyae Ann on Muck Rack

Jihyae Ann

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Structural anatomy of Protein Kinase C C1 domain interactions with diacylglycerol and other agonists - Nature Communications

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By Inna V. Krieger, Tatyana I. Igumenova, Jihyae Ann, Jeewoo Lee
| Nature Verified
Abstract Diacylglycerol (DAG) is a versatile lipid whose 1,2-sn-stereoisomer serves both as second messenger in signal transduction pathways that control vital cellular processes, and as metabolic precursor for downstream signaling lipids such as phosphatidic acid. Effector proteins translocate to available DAG pools in the membranes by using conserved homology 1 (C1) domains as DAG-sensing modules.
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