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Jillian F. Escobar on Muck Rack

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Zinc blocks SOS-induced antibiotic resistance via inhibition of RecA in Escherichia coli

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By Mark Sutton, Bryan E. Bunnell, Jillian F. Escobar, Kirsten L. Bair
| PLOS
Zinc inhibits the virulence of diarrheagenic E. coli by inducing the envelope stress response and inhibiting the SOS response. The SOS response is triggered by damage to bacterial DNA. In Shiga-toxigenic E. coli, the SOS response strongly induces the production of Shiga toxins (Stx) and of the bacteriophages that encode the Stx genes. In E.
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