Jin Sungho

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Suppression of endothelial ceramide de novo biosynthesis by Nogo-B contributes to cardiometabolic diseases - Nature Communications

Feb 24, 2025 |

By Jin Sungho, Alice Marino, Olivier Elemento, Sabrina Diano

| Nature

Abstract Accrual of ceramides, membrane and bioactive sphingolipids, has been implicated in endothelial dysfunction preceding cardiometabolic diseases. Yet, direct in vivo evidence, underlying mechanisms, and pathological implications are lacking.

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Jin Sungho

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Suppression of endothelial ceramide de novo biosynthesis by Nogo-B contributes to cardiometabolic diseases - Nature Communications

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