ORIGINAL ARTICLE Xiao-Xuan Ma, Ying Zhang and Jing-Si Jiang are contributed equally to this study. Abstract Diabetes mellitus (DM) can lead to diabetic ulcers (DUs), which are the most severe complications. Due to the need for more accurate patient classifications and diagnostic models, treatment and management strategies for DU patients still need improvement. The difficulty of diabetic wound healing is caused closely related to biological metabolism and immune chemotaxis reaction dysfunction.
