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Abstract The cytidine analog Azvudine (Azv) showed promising therapeutic effects against Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2) infections, leading to its conditional authorization as a COVID-19 treatment in China. Once Azvudine enters infected cells, it is converted to the active form, Azvudine-triphosphate, which has been shown to inhibit polymerases of several viruses.
New York, NY--April 21, 2016--Researchers from Columbia University, with colleagues at Genia Technologies (Roche), Harvard University and the National Institute of Standards and Technology (NIST) report achieving real-time single molecule electronic DNA sequencing at single-base resolution using a protein nanopore array. DNA sequencing is the key technology for personalized and precision medicine initiatives, enabling rapid discoveries in biomedical science.
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