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Jingzhang Li on Muck Rack

Jingzhang Li

As seen in: Nature, Heart, Lung and Circulation
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Articles

DUSP5 suppresses esophageal squamous cell carcinoma by counteracting macrophage-derived AREG-ERK1/2 signaling and disrupting an oncogenic ERK1/2-ELK1-DUSP5 feedback circuitry

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By Xu Feng Huang, Wenyi Xu, Junjie Kuang, Kai Zhu, Jun Li, Jingzhang Li, Yavuz Nuri Ertas, Maojin Tian, Miao Lin, Runze You, Qiuhong Ma
| Nature Verified
Abstract Dual-specificity phosphatase 5 (DUSP5) is a key regulator of the mitogen-activated protein kinase (MAPK) pathway, with established roles in various types of cancer. However, its function in esophageal squamous cell carcinoma (ESCC) remains unclear. This study combines single-cell transcriptomics with in vitro and in vivo models to investigate the role of DUSP5 in ESCC.
Open in Who Shared Issue with article?

Influence of Dynamic and Static Obstructive Renal Artery on Early Prognosis in Standford Type A Aortic Dissection

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By Xin Pu, Maozhou Wang, Jingzhang Li, Menghui Xu
| Heart, Lung and Circulation Verified
Background Acute kidney injury (AKI) after acute Stanford type A aortic dissection (STAAD) surgery has a high mortality rate. Clarifying what type of renal artery problem (dynamic obstructive renal artery, DORA, or static obstructive renal artery, SORA) secondary to STAAD benefits from true lumen opening is helpful in providing a reference for the indication of renal artery intervention.
Open in Who Shared Issue with article?
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