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Articles by Jinping Li
Glutathione S transferase assembled gold silver nanoclusters activate cGAS STING immunity in breast cancer
Abstract Breast cancer often returns or spreads after treatment, and therapies that can destroy tumors while also engaging the immune system are urgently needed. However, it remains difficult to design safe nanomaterials that both heat tumors under light and turn dying cancer cells into signals that support long-lasting antitumor immunity.
Metaplastic breast carcinoma versus triple-negative breast cancer: distinct metastatic patterns and inferior overall survival in a matched retrospective cohort study
Abstract Background: Metaplastic breast carcinoma (MBC) is an uncommon invasive breast cancer subtype with marked morphological diversity. Many MBCs are managed within the triple-negative breast cancer (TNBC) framework, yet their clinical course may not mirror that of non-metaplastic TNBC. We therefore compared clinicopathological features, recurrence and metastatic patterns, and survival outcomes in patients with MBC and those with non-metaplastic TNBC.
Association of finerenone with graded proteinuria improvement in type 2 diabetes with chronic kidney disease and proteinuria >1 g/d: a retrospective cohort study
Abstract Background: Current evidence for finerenone in T2DM with CKD is derived primarily from patients with microalbuminuria to macroalbuminuria, and data in those with moderate-to-heavy proteinuria remain limited. This study aimed to investigate the effect of finerenone on sustained graded improvement of 24h-UTP and its safety profile in T2DM patients with CKD and proteinuria >1 g/d.
Hydrogen bond mediated oxidation enables sustained oxygen evolution at industrial current densities
Abstract Stable and efficient non−precious electrocatalysts are crucial for the industrialization of anion exchange membrane water electrolysis as a green hydrogen production technology. Here, we show a synergistic dual-anion engineering combining Se doping and surface [B(OH)4]− modification to overcome the activity-stability trade-off in NiFe (oxy)hydroxide.
Decision-Making Readiness and Its Influencing Factors Among Lung Cancer Patients Receiving Chemotherapy: A Cross-Sectional Study
1 Introduction Lung cancer is the most commonly diagnosed malignancy worldwide, with China reporting over 1 million new cases and 740,000 deaths in 2022, making it the leading cause of cancer-related morbidity and mortality in the country (Bray et al. 2022; Han et al. 2024). As a cornerstone of lung cancer management, chemotherapy is widely applied not only in advanced or metastatic stages but also as neoadjuvant and adjuvant therapy (Ettinger et al. 2019).
Sequential ethane filling induced structural transitions in a flexible–robust metal–organic framework for ethylene purification
Abstract The preferential identification of inert ethane molecules and the corresponding pore-filling mechanism are fundamentally challenging. Although flexible metal–organic frameworks are considered promising candidates to enhance ethane selectivity, their gate-opening pressures for ethane and ethylene are usually similar, which limits further improvement in their separation performance.
Feature-based clustering of hemoglobin trajectories and subsequent risk of end-stage kidney disease in stages 3–4 CKD: a landmark analysis
Abstract Background: Anemia and protein-energy wasting (PEW) are common complications in chronic kidney disease (CKD) and are associated with disease progression. However, the prognostic significance of longitudinal hemoglobin (Hb) trajectory patterns, particularly in the context of nutritional status, remains unclear.
Authentic Leadership and Job Embeddedness Among Clinical Nurses: Mediating Roles of Perceived Insider Status and Organisational Identification
1 Introduction The global healthcare system is experiencing an intensifying nursing shortage driven by shifting care models and rapidly aging populations (World Health Organization [WHO] 2020). The World Health Organization (WHO) estimates that the worldwide deficit of nurses may reach 6 million by 2030 (World Health Organization [WHO] 2020).
Sevoflurane Preconditioning Mitigates Hypoxia and Reoxygenation Injury in Cardiomyocytes Through microRNA‐451a Regulation
Conflicts of Interest The authors declare no conflicts of interest. Data Availability Statement The data that support the findings of this study are available from the corresponding author upon reasonable request. References 1, , , and , “Mesenchymal Stem Cell-Derived Exosomes in Cardiovascular and Cerebrovascular Diseases: From Mechanisms to Therapy,” Biomedicine & Pharmacotherapy 163 (2023): 114817.
Advancing renewable energy sustainability: a deep dive into predictive modelling of wind energy output using machine learning algorithms and hyperparameter optimization
Advanced search Australian Journal of Electrical and Electronics Engineering Latest Articles Submit an article Journal homepage Full Article Figures & data References Citations Metrics Reprints & Permissions Read this article /doi/full/10.1080/1448837X.2025.2598495?needAccess=true ABSTRACT Global warming presents an urgent need for renewable energy adoption, exemplified by Denmark’s success in generating over 50% of its electricity from renewables, primarily wind power.
Sandwiching of MOF nanoparticles between graphene oxide nanosheets among ice grains - Nature Communications
Abstract Current strategies to tailor the formation of nanoparticle clusters require specificity and directionality built into the surface functionalization of the nanoparticles by involved chemistries that can alter their properties. Here, we describe a non-disruptive approach to place nanomaterials of different shapes between nanosheets, i.e., nano-sandwiches, absent any pre-modification of the components.
Lymphocyte-to-C-reactive protein ratio predicts prognosis in unresectable locally advanced non-small cell lung cancer patients
Abstract Background The lymphocyte-to-C-reactive protein ratio (LCR) is a promising inflammation-based tool for assessing the status of patients with malignant tumours. This study evaluated the ability of LCR to predict the prognosis of patients with unresectable locally advanced non-small cell lung cancer (LA-NSCLC) after chemoradiotherapy.
Low-Dark-Current and Wide-Dynamic-Range InGaAs/InAlAs Avalanche Photodiodes with a Dual-Charge Layer
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Influence of Additives on Solar-Controlled Anaerobic and Aerobic Processes of Cow Manure and Tomato Waste
All articles published by MDPI are made immediately available worldwide under an open access license. No special permission is required to reuse all or part of the article published by MDPI, including figures and tables. For articles published under an open access Creative Common CC BY license, any part of the article may be reused without permission provided that the original article is clearly cited. For more information, please refer to https://www.mdpi.com/openaccess.
Preparation of Ionic Polymer-Metal Composites Using Copper Electrodes via Magnetron Sputtering
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Enhancing CO2-facilitated transport of PVAm membrane by the synergistic effect of porous molybdenum disulfide and mobilizable sulfonic groups
Enhancing CO2-facilitated transport of PVAm membrane by the synergistic effect of porous molybdenum disulfide and mobilizable sulfonic groups The interlayer spacing of molybdenum disulfide nanosheets (MoS2) can form gas transport channels in mixed matrix membranes, but its tortuous passageway suppresses an increase in the permeance and selectivity simultaneously.
Effectiveness of Spent Coffee Ash in Concrete Permeable Pavement Bricks
Get full access to this article View all available purchase options and get full access to this article. Data Availability Statement All data, models, and code generated or used during the study appear in the published paper. Acknowledgments This study was supported by the General Project of Natural Science Foundation of Shaanxi Province (2022JM-293) and the Project of Basic Research Operating Costs of Central Universities (300102213511).
A Flexible Metal‐Organic Framework for the removal of propyne from propylene
Supporting Information As a service to our authors and readers, this journal provides supporting information supplied by the authors. Such materials are peer reviewed and may be re-organized for online delivery, but are not copy-edited or typeset. Technical support issues arising from supporting information (other than missing files) should be addressed to the authors.
Parameters Affecting Seismic Performance of Longitudinally Connected Track Lateral Blocks on Bridges Under Low-Cycle Reciprocating Loads
1. Introduction Currently, in the context of seismic analysis of the track–bridge system, the focus has primarily been on transverse residual deformation caused by earthquakes and its effect on the operational safety of the railway system both during and after seismic events [1].
Electric Vehicle Charging Load Demand Forecasting in Different Functional Areas of Cities with Weighted Measurement Fusion UKF Algorithm
All articles published by MDPI are made immediately available worldwide under an open access license. No special permission is required to reuse all or part of the article published by MDPI, including figures and tables. For articles published under an open access Creative Common CC BY license, any part of the article may be reused without permission provided that the original article is clearly cited. For more information, please refer to https://www.mdpi.com/openaccess.
Utilization Potential of Aerated Concrete Block Powder and Coffee Grounds Ash in Green-Growing Concrete
All articles published by MDPI are made immediately available worldwide under an open access license. No special permission is required to reuse all or part of the article published by MDPI, including figures and tables. For articles published under an open access Creative Common CC BY license, any part of the article may be reused without permission provided that the original article is clearly cited. For more information, please refer to https://www.mdpi.com/openaccess.
A Formulation Model to Compute the Life Cycle Environmental Impact of NiZn Batteries from Cradle to Grave
All articles published by MDPI are made immediately available worldwide under an open access license. No special permission is required to reuse all or part of the article published by MDPI, including figures and tables. For articles published under an open access Creative Common CC BY license, any part of the article may be reused without permission provided that the original article is clearly cited. For more information, please refer to https://www.mdpi.com/openaccess.
Leu promotes C2C12 cell differentiation by regulating the GSK3β/β‐catenin signaling pathway through facilitating the interaction between SESN2 and RPN2
Background Leucine (Leu), an essential amino acid that facilitated skeletal muscle satellite cell differentiation, yet its mechanism remained underexplored. Sestrin2 (SESN2) served as a Leu sensor, binding directly to Leu, while Riboprotein II (RPN2) acted as a signaling factor in multiple pathways.
Peritoneal Phosphate Clearance: Determinants and Association With Mortality
Data Availability Statement This paper contains all of the data generated or analyzed during the study. Any further queries should be directed to the corresponding author.
Autophagy regulates the maturation of hematopoietic precursors in the embryo - Nature Communications
Abstract An understanding of the mechanisms regulating embryonic hematopoietic stem cell (HSC) development would facilitate their regeneration. The aorta-gonad-mesonephros region is the site for HSC production from hemogenic endothelial cells (HEC). While several distinct regulators are involved in this process, it is not yet known whether macroautophagy (autophagy) plays a role in hematopoiesis in the pre-liver stage.
MPPT Strategy of Waterborne Bifacial Photovoltaic Power Generation System Based on Economic Model Predictive Control
All articles published by MDPI are made immediately available worldwide under an open access license. No special permission is required to reuse all or part of the article published by MDPI, including figures and tables. For articles published under an open access Creative Common CC BY license, any part of the article may be reused without permission provided that the original article is clearly cited. For more information, please refer to https://www.mdpi.com/openaccess.
Adaptive Deep Clustering Network for Retinal Blood Vessel and Foveal Avascular Zone Segmentation
1. Introduction Clear vision is essential for a fulfilling life, and retinal biomarkers are critical for identifying and diagnosing retinal disorders. These biomarkers offer valuable insights into human vision and can advance our understanding of retinal health [1]. RV and FAZ are crucial biomarkers that ophthalmologists use to diagnose and monitor retinal disease patients.
Energies | Free Full-Text | Numerical Investigation of a Solar-Heating System with Solar-Tower Receiver and Seasonal Storage in Northern China: Dynamic Performance Assessment and Operation Strategy Analysis
Abstract : Solar-heating technology is a promising solution to help China achieve the “3060 double carbon” target as soon as possible. Seasonal thermal storage (STS) can effectively solve the mismatch problem of solar-heating systems between the supply and demand of thermal energy. Due to the instability of solar radiation resources and the heat demand, it is necessary to analyze the dynamic response characteristics and operation strategy optimization of the system in different operation stages.
RuO2 nanoparticles anchored on g-C3N4 as an efficient bifunctional electrocatalyst for water splitting in acidic media
RuO2 nanoparticles anchored on g-C3N4 as an efficient bifunctional electrocatalyst for water splitting in acidic media Yun Wu, Rui Yao, Qiang Zhao, Jinping Li and Guang Liu Abstract The electrolysis of water, particularly the proton exchange membrane (PEM) water electrolysis, holds great promise for hydrogen production in industry.
A Comprehensive Prediction Model Based on MRI Radiomics and Clinical Factors to Predict Tumor Response After Neoadjuvant Chemoradiotherapy in Rectal Cancer
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Contrast-Enhanced CT Imaging Features Combined with Clinical Factors to Predict the Efficacy and Prognosis for Transarterial Chemoembolization of Hepatocellular Carcinoma
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Efficacy of XF-73 against Antibiotic-Resistant Bacteria
Introduction Skin and soft tissue infections (SSTIs) are some of the most common bacterial infections. Many bacteria and fungi species reside on the surface of human skin which are usually prevented from entering the body by the intact skin barrier and do not pose a threat of infection. However, in the case of skin damage, bacteria may invade the skin and subcutaneous tissue to cause infection. SSTIs are mainly caused by Gram-positive bacteria, especially S. aureus.
Functional Analysis of Bna-miR399c-PHO2 Regulatory Module Involved in Phosphorus Stress in Brassica napus
This is an early access version, the complete PDF, HTML, and XML versions will be available soon.
Radioimmunotherapy study of 131I-labeled Atezolizumab in preclinical models of colorectal cancer - EJNMMI Research
Expression levels of PD-L1 in human colorectal cancer cells (1) The relative expression levels of PD-L1 in four colorectal cancer cell lines (RKO, DLD-1, HCT8 and Caco-2) were determined by flow cytometry (Fig. 1a, b). The RKO cell line expressed higher levels of PD-L1, and the other three cell lines showed lower levels of PD-L1 expression.
Preparation of an interpenetrating bimetal metal-organic framework via metal metathesis used for promoting gas adsorption
Preparation of an interpenetrating bimetal metal-organic framework via metal metathesis used for promoting gas adsorption Feifei Zhang, Yingying Zhang, Xiaoqing Wang, Jinping Li and Jiangfeng Yang Abstract Metal-organic frameworks (MOFs), which allow precise control over their porous environment, have attracted extensive research attention in the field of gas adsorption.
Boosting the Photoactivity of BiVO4 Photoanodes by a ZnCoFe‐LDH Thin Layer for Water Oxidation
Full Paper Dr. Xiaojiang Wen, Shanxi Key Laboratory of Gas Energy Efficient and Clean Utilization, College of Chemistry and Chemical Engineering, Taiyuan University of Technology, Taiyuan, Shanxi 030024 P. R. China Search for more papers by this author Dr. Mengmeng Fan, Shanxi Key Laboratory of Gas Energy Efficient and Clean Utilization, College of Chemistry and Chemical Engineering, Taiyuan University of Technology, Taiyuan, Shanxi 030024 P. R. China Search for more papers by this author Prof.
Dynamical Analysis of Standing Balance Control on Sloped Surfaces in Individuals with Lumbar Disc Herniation
Abstract The changes of balance control mechanism caused by lumbar disc herniation (LDH) has not been well understood. This study aimed to investigate the effects of LDH on the balance control during standing on sloped surfaces. Ten patients with LDH and 10 gender- and age-matched healthy subjects were instructed to stand quietly on a sloped surface at −5°, 0° or +5°, respectively. The trajectories of the center of pressure (COP) of each individual limb and the full-body were recorded.
S-Doped Three-dimensional Graphene (S-3DG)： A metal-free Electrocatalyst for Electrochemical synthesis of Ammonia under Ambient Conditions
S-Doped Three-dimensional Graphene (S-3DG)： A metal-free Electrocatalyst for Electrochemical synthesis of Ammonia under Ambient Conditions In this work, we report sulfur doped three-dimensional graphene (S-3DG) as a metal-free electrocatalyst for N2 reduction reaction (NRR) under ambient conditions. Due to the high electron transport capacity and stable physicochemical properties of 3DG which utilized to improve the NRR catalytic performance dramatically.
Effect of Initial Pressure on the Formation of Carbon Dioxide Hydrate in Frozen Quartz Sand
Xuemin Zhang* Xuemin Zhang Western China Research Center of Energy & Environment, Lanzhou University of Technology, Lanzhou 730050, China Key Laboratory of Gas Hydrate, Guangzhou Institute of Energy Conversion, Chinese Academy of Sciences, Guangzhou 510640, China *E-mail: . Phone/Fax: +86 931 2976 332.
Inhibition of Sodium Glucose Cotransporter 2 Attenuates the Dysregulation of Kelch-Like 3 and NaCl Cotransporter in Obese Diabetic Mice
Patients with type 2 diabetes often exhibit salt-sensitive hypertension, but the mechanisms underlying this association remain unclear. One potential link, Kelch-like 3 (KLHL3), regulates BP by targeting the serine/threonine kinases with-no-lysines (WNKs) for degradation, thereby modulating activity of the NaCl cotransporter (NCC). The authors previously found that phosphorylation at serine 433 (S433) in KLHL3 downregulates KLHL3 activity.
Inhibition of Sodium Glucose Cotransporter 2 Attenuates the Dysregulation of Kelch-Like 3 and NaCl Cotransporter in Obese Diabetic Mice
Patients with type 2 diabetes often exhibit salt-sensitive hypertension, but the mechanisms underlying this association remain unclear. One potential link, Kelch-like 3 (KLHL3), regulates BP by targeting the serine/threonine kinases with-no-lysines (WNKs) for degradation, thereby modulating activity of the NaCl cotransporter (NCC). The authors previously found that phosphorylation at serine 433 (S433) in KLHL3 downregulates KLHL3 activity.
Physiopathological factors affecting the diagnostic value of serum HE4-test for gynecologic malignancies
Expert commentary : Studies have shown that physiopathological factors such as age, infection/inflammation, renal function, menopause and hormonal levels impose significant impacts on HE4 serum levels. HE4 amount shed into the circulation is related to HE4 expression and secretion by tumor as well as normal tissues, which is affected by cancer heterogeneity, vascular permeability, renal clearance and HE4 degradation.
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