Jinseob Lee on Muck Rack

Jinseob Lee

As seen in: Nature
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Articles

smDeepFLUOR: single-molecule deep learning fluorescence classification

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By Jinseob Lee, Byungju Kim, Gayun Bu, Muhammad Tehseen, Vlad-Stefan Raducanu, Samir M Hamdan, Jong-Bong Lee
| Nature Verified
Abstract Fluorescence intensity variation has long served as a primary readout for monitoring biological events. However, single-fluorophore signals arising from distinct molecular events often exhibit similar intensity profiles, making further classification challenging using conventional methods.
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Single-trajectory Bayesian modeling reveals multi-state diffusion of the MSH sliding clamp

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By Seongyu Park, Inho Yang, Jinseob Lee, Sinwoo Kim, Juana Martin-Lopez, Richard Fishel, Jong-Bong Lee, Jae-Hyung Jeon
| Nature Verified
Abstract DNA mismatch repair (MMR) is an essential mechanism for preserving genomic integrity across diverse living organisms. In this process, MutS homologs (MSH) play crucial roles in detecting mismatched basepairs and recruiting downstream MMR proteins. MSH exhibits distinct functions and diffusion dynamics before and after mismatch recognition.
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smDeepFLUOR: Single-Molecule Deep Learning Fluorescence Classification

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By Byungju Kim, Gayun Bu, Muhammad Tehseen, Jinseob Lee
| biorxiv.org
Abstract Fluorescence intensity variation has long served as a primary readout for monitoring biological events. However, single-fluorophore signals arising from distinct molecular events often exhibit similar intensity profiles, making further classification challenging using conventional methods.
Open in Who Shared Issue with article?
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