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Jinwen Zhou on Muck Rack

Jinwen Zhou

As seen in: Frontiers in Physiology, MDPI
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Articles

Precision-cut tumor slices: a biomimetic tool for accelerating oncological development from basic research to clinical translation

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By Xiaojun Lei, Song Bao, Dong Jin, Jinwen Zhou, Tao Guo, Jing Kong
| Frontiers in Physiology
Abstract Faithfully recapitulating the complex pathology of human tumors is a critical requirement for effective cancer research. However, animal models are limited by interspecies differences, and traditional in vitro systems often fail to maintain the native tissue architecture. Precision-cut tissue slices that retain the original tissue’s histology, cellular heterogeneity, and physiological functions offer a compelling alternative.
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Biomechanical Properties of the Aortic Wall: Changes during Vascular Calcification

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By Anna Maria Greco, Jinwen Zhou, Manasa Reddy Gummi, Milen Babic
| MDPI
Abstract : Medial vascular calcification (MAC) is characterized by the deposition of hydroxyapatite (HAP) in the medial layer of the vessel wall, leading to disruption of vessel integrity and vascular stiffness. Because currently no direct therapeutic interventions for MAC are available, studying the MAC pathogenesis is of high research interest. Several methods exist to measure and describe the pathophysiological processes in the vessel wall, such as histological staining and gene expression.
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