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As a journalist, you can create a free Muck Rack account to customize your profile, list your contact preferences, and upload a portfolio of your best work.Articles
Analytical solution of driven time-dependent mesoscopic circuits
Abstract When a time-dependent harmonic system is further driven by an external source, it presents significant challenges to obtaining analytical solutions for the system. This paper applies the Lewis-Riesenfeld invariant method to a mesoscopic time-dependent dissipative inductor-capacitor (RLC) circuit with an external source.
Cryo-EM structures of Candida albicans Cdr1 reveal azole-substrate recognition and inhibitor blocking mechanisms - Nature Communications
Abstract In Candida albicans, Cdr1 pumps azole drugs out of the cells to reduce intracellular accumulation at detrimental concentrations, leading to azole-drug resistance. Milbemycin oxime, a veterinary anti-parasitic drug, strongly and specifically inhibits Cdr1. However, how Cdr1 recognizes and exports azole drugs, and how milbemycin oxime inhibits Cdr1 remain unclear.
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