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Jiye Yin

As seen in: Nature, Wiley Online Library
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Articles

Mitochondrial calcium influx-driven bioenergetics selectively enable drug addiction

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By Jun Gao, Haixin Zhao, Xiao Han, Lingmin Zeng, Jingqi Pan, Guangqin Liu, Changwei Liu, Wenjun Wu, Siqi Chen, Jiayi Chen, Ting Li, Jiye Yin, Tao Zhou, Xue-Min Zhang, Ai-Ling Li, Xin Pan, Xuechen Wei
| Nature Verified
Abstract Addictive substances hijack the brain’s reward system, driving pathological dopamine surges that underlie compulsive behavior and addiction. However, directly targeting dopamine signaling for treatment risks disrupting natural reward processes. Here we identify a bioenergetic mechanism that selectively promotes addiction-related dopamine release and behaviors.
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CSDE1 depletion inhibits tumor progression through enhancing B-cell infiltration in NSCLC - Cell Death & Disease

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By Jiajia Cui, Jiye Yin
| Nature Verified
Abstract Although most immunotherapy research focuses on T cells, increasing evidence highlights the significant role of tumor-infiltrating B lymphocytes (TIL-Bs) in cancer therapy. CSDE1 has been implicated in various cancers and immune responses. This study investigates the role of CSDE1 in lung cancer progression and its impact on the tumor immune microenvironment. We found that CSDE1 promotes lung cancer progression in vivo but not in vitro.
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The binding profile of SARS‐CoV‐2 with human leukocyte antigen polymorphisms reveals critical alleles involved in immune evasion

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By Yan Zhan, Qianying Ouyang, Jiye Yin, Jiajia Cui
| Wiley Online Library Verified
CONFLICT OF INTEREST STATEMENT The authors declare no conflict of interest. Supporting Information Filename Description jmv29113-sup-0001-Figure_legends_for_supplementary_data.docx18.2 KB Supporting information. jmv29113-sup-0002-Figure_S1_1.tif515 KB Supporting information. jmv29113-sup-0003-Figure_S2_1.tif7.5 MB Supporting information. jmv29113-sup-0004-Figure_S3_1.tif3.5 MB Supporting information. jmv29113-sup-0005-Supplementary_tables.docx64.6 KB Supporting information. REFERENCES 1, , , , .
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