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Joanna Bartkiewicz on Muck Rack

Joanna Bartkiewicz

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Articles

Patterns of phosphorylated tau accumulation in a spectrum of acquired and developmental brain lesions associated with refractory epilepsy

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By Alicja Mrzyglod, Anya Mebrouk, Joanna Bartkiewicz, Hanaa El Hachami
| Wiley Online Library Verified
There is interest in the role of pTau in epileptogenesis and memory impairment in patients with epilepsy. In varied developmental and acquired epilepsy surgical pathologies, we noted low to moderate pTau in 60%, confirming variable phosphorylation sites. Vascular lesions showed more frequent localized pTau, which may implicate vascular deficiency or impaired clearance mechanisms. Superficial cortical pTau, including in some encephaloceles, could implicate injury and gliosis.
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