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Joanna Winkler on Muck Rack

Joanna Winkler

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Articles

Molecular architecture of the endocytic TPLATE complex

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By Jie Wang, Klaas Yperman, Dominique Eeckhout, Joanna Winkler
| Science Magazine Verified
Abstract Eukaryotic cells rely on endocytosis to regulate their plasma membrane proteome and lipidome. Most eukaryotic groups, except fungi and animals, have retained the evolutionary ancient TSET complex as an endocytic regulator. Unlike other coatomer complexes, structural insight into TSET is lacking. Here, we reveal the molecular architecture of plant TSET [TPLATE complex (TPC)] using an integrative structural approach.
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