Jodee Gould on Muck Rack

Jodee Gould

As seen in: Nature
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Articles

Patient-derived intestinal organoids as a model for site-specific mucosal bacterial interactions in paediatric inflammatory bowel disease

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By Eva Y. Chan, Stuart K Archer, Thierry Jardé, Jodee Gould, Shanika L. Amarasinghe, Emily L. Rutten, Gemma L. D’Adamo, Emily L. Gulliver, Samuel C. Forster, Edward M. Giles, Helen Abud, Genevieve Kerr, Rebekah M. Engel
| Nature Verified
Abstract Inflammatory bowel disease (IBD) is secondary to an abnormal immune response to the microbiota. To study this, models of host-microbe interactions that represent mucosal bacterial communities and inter-patient diversity are required. Human intestinal organoids (HIOs) are an established model to investigate epithelial responses. Here, we describe a technique of culturing bacteria directly from the sites of inflammation in IBD, while simultaneously sampling host tissue.
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Restoration of normal embryogenesis by mitochondrial supplementation in pig oocytes exhibiting mitochondrial DNA deficiency

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By Te-Sha Tsai, Yogeshwar Makanji, Pamela Matthews, Jodee Gould
| ncbi.nlm.nih.gov
Restoration of normal embryogenesis by mitochondrial supplementation in pig oocytes exhibiting mitochondrial DNA deficiency Gael L. M. Cagnone , 1,2,* Te-Sha Tsai , 1,2,* Yogeshwar Makanji , 1,2 Pamela Matthews , 1,2 Jodee Gould , 2,3 Michael S. Bonkowski , 4 Kirstin D. Elgass , 5 Ashley S. A. Wong , 6 Lindsay E. Wu , 6 Matthew McKenzie , 1,2 David A. Sinclair , 4 and Justin C. St. Johna,1,2 Gael L. M.
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