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Joel Frey

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Civil Air Patrol pilots take flight

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By Joel Frey
| The Enquirer-Journal Verified
MONROE, N.C. — The skies over Monroe were alive with excitement the first weekend in March as seven cadets from the Civil Air Patrol’s (CAP) Union County Composite Squadron (NC-300) took to the air for their cadet orientation fights. These flights, a cornerstone of CAP’s aerospace education program, offer young cadets hands-on flying experience in both gliders and powered aircraft.
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Nuclear actin polymerization rapidly mediates replication fork remodeling upon stress by limiting PrimPol activity - Nature Communications

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By Daniel González-Acosta, Jana Krietsch, Henriette Stoy, Svenja Ulferts, Joel Frey, Cyril Doerdelmann, Robert Grosse, Irene Chiolo, Maria Dilia Palumbieri, Danina Kuster, Thomas von Känel
| Nature Verified
Abstract Cells rapidly respond to replication stress actively slowing fork progression and inducing fork reversal. How replication fork plasticity is achieved in the context of nuclear organization is currently unknown. Using nuclear actin probes in living and fixed cells, we visualized nuclear actin filaments in unperturbed S phase and observed their rapid extension in number and length upon genotoxic treatments, frequently taking contact with replication factories.
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