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Johana Barrientos on Muck Rack

Johana Barrientos

As seen in: BioRxiv
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Articles

In vivo tracking of ex vivo generated 89Zr-oxine labeled plasma cells by PET in a non-human primate model

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By David Young, Abigail Edwards, Ella Liberzon, Johana Barrientos
| BioRxiv
Abstract B cells are an attractive platform for engineering to produce protein-based biologics absent in genetic disorders, and potentially for the treatment of metabolic diseases and cancer. As part of pre-clinical development of B cell medicines, we demonstrate a method to collect, ex vivo expand, differentiate, radioactively label, and track adoptively transferred non-human primate (NHP) B cells.
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