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Inhibition of high risk HPV31 E8^E2 repressor activity enables differentiation-independent genome amplification and E4 expression
Loading metrics Open Access Peer-reviewed Research Article ? This is an uncorrected proof. Citation: Rehm TM, Straub E, Doorbar J, Grundhoff A, Günther T, Blümke P, et al. (2026) Inhibition of high risk HPV31 E8^E2 repressor activity enables differentiation-independent genome amplification and E4 expression. PLoS Pathog 22(6): e1014330. https://doi.org/10.1371/journal.ppat.1014330 Editor: Cary A.
Risk factors for human papillomavirus infection and disease: A targeted literature summary
1 INTRODUCTION Human papillomavirus (HPV) infection is the most common sexually transmitted infection (STI) worldwide.1 While most HPV infections clear, some persist and may progress to premalignant lesions and cancer.2, 3 Globally, approximately 690 000 new cases of HPV-related cancer occurred in 2018, comprising mostly cervical cancer (approximately 570 000 cases).4 In addition, approximately 29 000 new anal, 11 000/14 000 new vulvar/vaginal, 18 000 new penile, and 42 000 new head and neck...
The human Papillomavirus twilight zone - Latency, immune control and subclinical infection
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